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Evidence-Based Orthodontics

Research Library

A curated collection of the studies that inform how Dr. Napoli diagnoses and treats — on airway health, palatal expansion, sleep, tongue posture, facial growth, and more.

Dr. Vince Napoli Dr. Vince Napoli Board-Certified Orthodontist

At Napoli Orthodontics, we believe orthodontics is about more than just straight teeth.

A beautiful smile matters, but so does the foundation behind it. That means looking at how the jaws grow, how the palate develops, how a child breathes, sleeps, swallows, and functions.

Our practice is built around evidence-based orthodontics, thoughtful diagnosis, and educating families on the “why” behind treatment. This page is a research library for patients who want to better understand topics like airway health, palatal expansion, tonsils and adenoids, tongue posture, sleep quality, facial growth, and more.

Because at Napoli Orthodontics, we are not just moving teeth. We are building smiles on a healthier generation.

— Dr. Vince Napoli

Browse the studies

Showing all 19 studies

Kids & Breathing

A Roadmap of Craniofacial Growth Modification for Children with Sleep-Disordered Breathing: A Multidisciplinary Approach

A review of how guiding jaw and facial growth early can ease sleep-disordered breathing in children — and why orthodontists, ENTs, and sleep physicians achieve better results working as a team.

Yoon A. — PMC, 2023 Read the study
Kids & Breathing

Impact of Rapid Palatal Expansion on the Size of Adenoids and Tonsils in Children

Widening a child’s palate not only made more room in the mouth but was associated with smaller adenoids and tonsils — two of the most common contributors to snoring and disrupted sleep.

PubMed, 2022 Read the study
Kids & Breathing

Craniofacial Anatomical Determinants of Pediatric Sleep-Disordered Breathing: A Comprehensive Review

A detailed look at how the size and shape of a child’s jaw, nasal passages, and airway contribute to sleep-disordered breathing — helping clinicians spot who needs more than tonsil removal.

Journal of Prosthodontics, 2024 Read the study
Kids & Breathing

Determinants of Probable Sleep Bruxism in a Pediatric Mixed Dentition Population: Mouth vs. Nasal Breathing, Tongue Mobility, and Tonsil Size

Children who breathe through the mouth, have limited tongue mobility, or enlarged tonsils were notably more likely to grind their teeth at night — tying nighttime grinding to airway function.

Sleep Medicine, 2021 Read the study
Kids & Breathing

Development of a Functional Airway Evaluation Screening Tool (FAIREST-6) During the Mixed Dentition

Researchers built a quick six-item screening tool to flag children at risk for sleep-disordered breathing during the years when baby and adult teeth overlap — enabling earlier, gentler treatment.

Pediatric Dentistry, 2021 Read the study
Maxillary Expansion

The Role of Rapid Maxillary Expansion in the Promotion of Oral and General Health

A landmark review showing that widening a narrow upper jaw does more than straighten teeth — it can improve nasal breathing, reduce mouth breathing, and benefit sleep and overall health.

McNamara JA — PMC, 2015 Read the study
Maxillary Expansion

Nasal Breathing Improvement Following Palatal Expansion

Documents measurable gains in nasal airflow after palatal expansion, reinforcing the rationale for using orthodontic expansion as part of a breathing-focused treatment plan.

Annals of ENT International, 2022 Read the study
Maxillary Expansion

Maxillary Expansion in the Management of Pediatric Obstructive Sleep Apnea

Reviews the evidence for using palatal expansion to treat obstructive sleep apnea in children, finding it reduces airway obstruction and can meaningfully ease symptoms — sometimes avoiding surgery.

Journal of Clinical Medicine, 2025 Read the study
Maxillary Expansion

The Effect of Rapid Maxillary Expansion on Children with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis

Pooling data across studies, this meta-analysis confirms expansion consistently reduces apnea severity in children, and suggests it as a first-line option when a narrow palate is involved.

Sleep and Breathing, 2026 Read the study
Maxillary Expansion

Expansion of the Nasal Passageway: Tooth-Borne Rapid Maxillary Expansion

Examines how traditional tooth-anchored expansion affects nasal airway dimensions, showing it produces real, measurable increases in the space available for nasal breathing.

PMC, 2017 Read the study
Maxillary Expansion

Nasal Airflow Changes Following Rapid Maxillary Expansion

A companion study measuring actual airflow after expansion — patients showed significant improvements in nasal breathing capacity, underscoring expansion as an airway intervention.

PubMed, 2017 Read the study
Maxillary Expansion

Skeletal and Dentoalveolar Effects of Tooth-Borne vs. Tooth-Bone-Borne RME: A Randomized Controlled Trial with 1-Year Follow-Up

A randomized trial comparing traditional and hybrid bone-anchored expanders over a year — bone-anchored designs produced more skeletal widening with less unwanted tooth tipping.

PubMed, 2020 Read the study
MARPE

Impact of Rapid Palatal Expansion on the Internal Nasal Valve and Obstructive Nasal Symptoms in Children

Focuses on the internal nasal valve — a key chokepoint for airflow — and shows expansion increases its cross-sectional area, directly reducing nasal congestion and obstruction in children.

Sleep and Breathing, 2020 Read the study
MARPE

MARPE vs. Conventional Expander: Nasal Airflow Changes

A direct comparison of mini-screw assisted expansion and traditional tooth-borne expanders. MARPE produced greater airway improvement by opening the skeletal suture more fully.

PMC, 2025 Read the study
MARPE

MARPE Effects on Adult Obstructive Sleep Apnea and Quality of Life: A Multi-Center Prospective Controlled Trial

One of the strongest studies supporting MARPE for adults with sleep apnea — participants showed reduced apnea severity and meaningful gains in sleep, daytime energy, and quality of life.

Progress in Orthodontics, 2021 Read the study
MARPE

Treatment Outcomes of 3D-Printed Custom vs. Conventional MARPE Appliances

Compares 3D-printed custom MARPE devices against conventional ones, finding both effective while custom-designed expanders offer a better fit — a look at how digital tools improve appliance precision.

PMC, 2025 Read the study
Jaw Surgery

Maxillomandibular Advancement for Treatment of Obstructive Sleep Apnea: A Meta-Analysis

A meta-analysis finding jaw-advancement surgery is among the most effective surgical treatments for sleep apnea, with high success rates even for patients who did not respond to CPAP.

JAMA Otolaryngology, 2016 Read the study
Jaw Surgery

Long-Term Results for Maxillomandibular Advancement to Treat Obstructive Sleep Apnea: A Meta-Analysis

Examines whether the benefits of jaw-advancement surgery last — patients maintained significant reductions in apnea severity years later, supporting it as a durable solution for the right candidates.

Otolaryngology–Head and Neck Surgery, 2019 Read the study
Myofunctional

Myofunctional Therapy to Treat Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis

Targeted exercises for the tongue, throat, and oral muscles reduced apnea severity by roughly half in adults and more in children — establishing myofunctional therapy as an evidence-based adjunct to care.

SLEEP, 2015 Read the study

This research informs the treatments Dr. Napoli offers and how he approaches care for every patient. If you're curious whether any of these findings apply to your situation, a consultation is the best place to start.

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